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If your platelet count is only slightly below normal, it shouldn’t cause you or your baby any problems and you won’t need any treatment. When your count dips to between 100 million and 150 million platelets per ml of blood, your doctor will diagnose mild gestational thrombocytopenia. But, for most women, the count is still in the normal range. Pregnancy naturally causes a slight fall in your platelet count, particularly if you’re expecting twins. On average, adults have between 150 million and 450 million platelets per millilitre (ml) of blood. Platelets are cells that help your blood to clot when it needs to. Your platelet count is usually checked during a routine blood test, taken at one of your antenatal appointments. It affects about one pregnant woman in 10 and usually develops in mid to late pregnancy. More so, there are several factors that could affect the result of mean platelet volume.If your platelet count drops below normal levels during pregnancy, it's most likely that you have a common pregnancy condition called gestational thrombocytopenia. Which is why it is important to take a look at other blood parameter readings so as to check whether or not there is indeed an abnormality or not. However, a high MPV does not always mean that there is an abnormality in the body.Ī low MPV does not always suggest abnormalities.
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It is different from platelet count but is closely related to it.Ī high MPV may have a low platelet count and the other way around. The mean platelet volume measures the size of the platelet. The mean platelet volume test is one of the parameters checked in a routine blood test. Bone marrow hypoplasia ( a disease caused by a decreased production of blood cells).Exposure to some type of drugs that could harm the cells (cytotoxic medication) usually drugs used for chemotherapy.Inflammatory bowel disease such as ulcerative colitis and Crohn’s disease.With the interpretation of other blood level parameters, a low mean platelet volume could indicate the following: They are old platelets, which means that the bone marrow has trouble producing new platelets. (6, 7, 8, and 9) MPV blood test lowĪn abnormally low mean platelet volume means that y our platelets are smaller than the average. Other possible conditions caused by a high mean platelet volume are heart-related disease, hyperthyroidism, diabetes, high blood pressure, vitamin D deficiency, diabetes, atrial fibrillation, stroke, and preeclampsia.
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It signals a reduced survival rate, especially in patients with lung cancer, colon cancer, ovarian cancer, cancer of the stomach and kidneys, pancreatic cancer, endometrial cancer, and breast cancer. On the other hand, if you have cancer and your mean platelet volume is high, it means that the cancer cells have already metastasized or spread to other body parts.
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If you have a family history of cancer or exhibiting signs and symptoms of cancer (abnormal changes in the breast, skin abnormalities, an abnormal lump under the skin, change in bowel habit, feeling weak, night sweat, unusual bleeding, and abnormal changes in bowel habit) your doctor might need to perform additional test to confirm the diagnosis. (4, 6) A high MPV can be linked with the following:Ī high MPV is linked with platelet activation as a result of an encounter of platelets to tumor by-products. However, if your MPV is high and your platelet count is low, it could indicate a possible bone marrow disorder (rapidly producing platelets) leading to the destruction of the older platelets. If the mean platelet volume is high, it means that your platelet is higher than the average, which means that you are producing too many platelets.